Acro‐Osteolysis in Rheumatic Diseases
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Review Article
Elena Bartoloni, Devid Biscontini, Alessia Alunno, Filippo Luccioli, Sheila Moscatelli, Gianluca Santoboni and Roberto Gerli
Affiliation: Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
ABSTRACT
Acro‐osteolysis (AO) has been reported in association with different systemic diseases. Pathogenesis is not completely understood, and several mechanisms leading to this destructive process have been hypothesized. In recent years, AO has been described in patients with chronic inflammatory rheumatic and connective tissue diseases, and different mechanisms contributing to bone damage have been postulated. This review will discuss possible pathogenetic mechanisms involved in bone resorption, focusing on the description of AO in patients with rheumatic diseases.
Keywords: acro‐osteolysis, rheumatic diseases, psoriatic arthritis
Correspondence: Roberto Gerli, Rheumatology Unit, Department of Clinical and Experimental Medicine, Via E Dal Pozzo, I-06122 Perugia, Italy. Tel: (39)-075-578-3975; Fax: (39)-075-578-3105; e-mail: gerlir@unipg.it
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